The Erythrocyte Sedimentation Rate and Its Relation to Cell Shape and Rigidity of Red Blood Cells from Chorea-Acanthocytosis Patients in an Off-Label Treatment with Dasatinib

Background: Chorea-acanthocytosis (ChAc) is a rare hereditary neurodegenerative disease with deformed red blood cells (RBCs), so-called acanthocytes, as a typical marker of the disease. Erythrocyte sedimentation rate (ESR) was recently proposed as a diagnostic biomarker. To date, there is no treatme...

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Detalhes bibliográficos

Principais autores:	Antonia Rabe, Alexander Kihm, Alexis Darras, Kevin Peikert, Greta Simionato, Anil Kumar Dasanna, Hannes Glaß, Jürgen Geisel, Stephan Quint, Adrian Danek, Christian Wagner, Dmitry A. Fedosov, Andreas Hermann, Lars Kaestner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-05-01
coleção:	Biomolecules
Assuntos:	acanthocytes dasatinib erythrocyte sedimentation rate 3D shapes microfluidics phase diagram
Acesso em linha:	https://www.mdpi.com/2218-273X/11/5/727
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