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LINC00162 silencing enhances sorafenib sensitivity and inhibits thyroid cancer cells progression through modulation of MAPK signaling and apoptosis

Abstract Many studies have reported the aberrant expression of lncRNAs and indicated their role in cancer progression and drug resistance across various cancers. In this study, we aimed to evaluate the effect of LINC00162 lncRNA on the chemosensitivity of thyroid cancer cells, both individually and...

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Auteurs principaux: Maryam Hejazi, Seyedeh Zahra Bahojb Mahdavi, Saba Abedimanesh, Ramin Heshmat, Bagher Larijani, Amir Ali Mokhtarzadeh, Gita Shafiee, Seyed Mohammad Tavangar
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2025-08-01
Collection:Scientific Reports
Sujets:
LINC00162
Thyroid Cancer
Sorafenib
Chemosensitivity
MAPK pathway
Apoptosis
Accès en ligne:https://doi.org/10.1038/s41598-025-12805-x
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