Antibodies targeting HSV glycoprotein B require effector functions to protect neonatal mice

ABSTRACT Glycoprotein B (gB) serves as the viral fusion protein for herpes simplex virus (HSV), mediating fusion between viral and host membranes resulting in infection. As such, gB represents a critical target for the host immune system with high potential relevance for vaccine design. Here, we inv...

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Principais autores:	Matthew D. Slein, Lesle M. Jiménez, Iara M. Backes, Evelyn M. Turnbaugh, Callaghan R. Garland, Scott W. MacDonald, Alejandro B. Balazs, David A. Leib, Margaret E. Ackerman
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2026-04-01
Series:	Journal of Virology
Assuntos:	antibody herpesvirus effector function neutralization mechanism neonatal
Acceso en liña:	https://journals.asm.org/doi/10.1128/jvi.00050-26
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