The protein aggregation inhibitor YAT2150 has potent antimalarial activity in Plasmodium falciparum in vitro cultures

Abstract Background By 2016, signs of emergence of Plasmodium falciparum resistance to artemisinin and partner drugs were detected in the Greater Mekong Subregion. Recently, the independent evolution of artemisinin resistance has also been reported in Africa and South America. This alarming scenario...

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Váldodahkkit:	Inés Bouzón-Arnáiz, Yunuen Avalos-Padilla, Arnau Biosca, Omar Caño-Prades, Lucía Román-Álamo, Javier Valle, David Andreu, Diana Moita, Miguel Prudêncio, Elsa M. Arce, Diego Muñoz-Torrero, Xavier Fernàndez-Busquets
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2022-10-01
Ráidu:	BMC Biology
Fáttát:	Plasmodium falciparum Protein aggregation YAT2150 Amyloid pan-inhibitors Malaria Antimalarial drugs
Liŋkkat:	https://doi.org/10.1186/s12915-022-01374-4
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