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9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts

Retinoic acid (RA) therapy has been utilized as maintenance therapy for high-risk neuroblastoma, but over half of patients treated with RA relapse. Neuroblastoma stem cell-like cancer cells (SCLCCs) are a subpopulation of cells characterized by the expression of the cell surface marker CD133 and are...

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Principais autores: Raoud Marayati, Laura V. Bownes, Laura L. Stafman, Adele P. Williams, Colin H. Quinn, Venkatram Atigadda, Jamie M. Aye, Jerry E. Stewart, Karina J. Yoon, Elizabeth A. Beierle
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-01-01
Colecção:Translational Oncology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1936523320303855
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