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A Unique P450 Peroxygenase System Facilitated by a Dual-Functional Small Molecule: Concept, Application, and Perspective

Cytochrome P450 monooxygenases (P450s) are promising versatile oxidative biocatalysts. However, the practical use of P450s in vitro is limited by their dependence on the co-enzyme NAD(P)H and the complex electron transport system. Using H<sub>2</sub>O<sub>2</sub> simplifies the catalytic cycle of P4...

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Autori principali: Siyu Di, Shengxian Fan, Fengjie Jiang, Zhiqi Cong
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-03-01
Serie:Antioxidants
Soggetti:
cytochrome P450 monooxygenase
peroxygenase
peroxidase
protein engineering
oxidation
hydroxylation
Accesso online:https://www.mdpi.com/2076-3921/11/3/529
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