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Immunogenicity of Monoclonal Antibodies and the Potential Use of HLA Haplotypes to Predict Vulnerable Patients

The use of monoclonal antibodies (mAbs) in the clinic has successfully expanded to treatment of cancer, viral infections, inflammations, and other indications. However, some of the classes of mAbs that are used in the clinic show the formation of anti-drug antibodies (ADAs) leading to loss of effica...

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Principais autores: Romy Mosch, Henk-Jan Guchelaar
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-06-01
Serija:Frontiers in Immunology
Teme:
Online dostop:https://www.frontiersin.org/articles/10.3389/fimmu.2022.885672/full
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