Investigation of Antibody Tolerance in Methanol for Analytical Purposes: Methanol Effect Patterns and Molecular Mechanisms

Abstract The extraction of targets from biological samples for immunoassays using organic solvents, such as methanol, is often necessary. However, high concentrations of organic solvents in extracts invariably lead to instability of the employed antibody, resulting in poor performance of the immunoa...

Full description

Bibliographic Details

Main Authors:	Yingjie Zhang, Jiafei Mi, Weilin Wu, Jie Fei, Bochen Lv, Xuezhi Yu, Kai Wen, Jianzhong Shen, Zhanhui Wang
Format:	Artigo
Language:	Inglês
Published:	Wiley 2024-08-01
Series:	Advanced Science
Subjects:	antibody methanol effect patterns antibody tolerance folding and aggregation immunoassay molecular mechanism
Online Access:	https://doi.org/10.1002/advs.202402050
Tags:	Add Tag No Tags, Be the first to tag this record!