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An ATM-CHK2-INCENP pathway prevents chromatin breakage by regulating the abscission checkpoint

In response to chromatin bridges, the chromosomal passenger complex (CPC) delays completion of cytokinesis (abscission) to prevent chromosome breakage. Here, we discuss recent findings from our lab showing that an ATM-CHK2-INCENP pathway imposes the abscission checkpoint in human cells by regulating...

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Bibliográfalaš dieđut
Váldodahkkit: Eleni Petsalaki, George Zachos
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Taylor & Francis Group 2021-03-01
Ráidu:Molecular & Cellular Oncology
Fáttát:
Liŋkkat:http://dx.doi.org/10.1080/23723556.2021.1877999
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