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Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains[S]

Vascular damage caused by Shiga toxin (Stx)-producing Escherichia coli is largely mediated by Stxs, which in particular, injure microvascular endothelial cells in the kidneys and brain. The majority of Stxs preferentially bind to the glycosphingolipid (GSL) globotriaosylceramide (Gb3Cer) and, to a l...

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Principais autores: Josefine Betz, Martina Bielaszewska, Andrea Thies, Hans-Ulrich Humpf, Klaus Dreisewerd, Helge Karch, Kwang S. Kim, Alexander W. Friedrich, Johannes Müthing
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2011-04-01
Serier:Journal of Lipid Research
Fag:
glycolipid
caveolae
DRM
Gb3Cer
Gb4Cer
caveolin-1
Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520408971
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