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Dysregulated metabolism of ceramides and glycosphingolipids in Parkinson’s disease

Alterations in sphingolipid metabolism have been implicated in the pathogenesis of Parkinson's disease (PD), yet findings regarding peripheral sphingolipid changes remain inconsistent. This study aimed to elucidate the metabolic profiles of plasma ceramides and glycosphingolipids (GSLs) in patients...

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Principais autores: Yu-Fong Peng, Szu-Ju Chen, Jeng-Lin Li, Chin-Hsien Lin, Ching-Hua Kuo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-01-01
coleção:Journal of Lipid Research
Assuntos:
Parkinson’s disease
sphingolipids
glycosphingolipids
ceramides
glucosylceramides
lactosylceramides
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227525002184
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