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Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse

Through their ability to regulate gene expression in most organs, glucocorticoid (GC) hormones influence numerous physiological processes and are therefore key regulators of organismal homeostasis. In bone, GC hormones inhibit expression of the hormone Osteocalcin for poorly understood reasons. Here...

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Autors principals: Vijay K. Yadav, Julian M. Berger, Parminder Singh, Perumal Nagarajan, Gerard Karsenty
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2022-02-01
Col·lecció:The Journal of Clinical Investigation
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Accés en línia:https://doi.org/10.1172/JCI153752
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