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Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma

Cancer stem cells (CSCs) drive tumour spread and therapeutic resistance, and can undergo epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) to switch between epithelial and post-EMT sub-populations. Examining oral squamous cell carcinoma (OSCC), we now show tha...

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主要な著者: Adrian Biddle, Luke Gammon, Xiao Liang, Daniela Elena Costea, Ian C. Mackenzie
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2016-02-01
シリーズ:EBioMedicine
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2352396416300056
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