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Interleukin-6 accelerates the progression of warm autoimmune hemolytic anemia by affecting the DNA methylation status of peripheral blood B lymphocytes

Abstract DNA methylation of peripheral blood (PB) B cells of warm autoimmune hemolytic anemia (wAIHA) patient was investigated. B cell DNA methylation level and the methylation-regulatory genes mRNA from 34 wAIHA patients and 16 healthy controls (HCs) were detected. The correlation between B cell DN...

Deskribapen osoa

Gorde:
Egile Nagusiak: Manjun Zhao, Yang Zhang, Zhaoyun Liu, Rong Fu, Huaquan Wang, Zonghong Shao, Limin Xing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-11-01
Saila:Scientific Reports
Gaiak:
Autoimmune hemolytic anemia
B lymphocytes
DNA methylation
IL-6
DNMT1
Sarrera elektronikoa:https://doi.org/10.1038/s41598-025-29813-6
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