Kindlins, integrin activation and the regulation of talin recruitment to αIIbβ3.

Talins and kindlins bind to the integrin β3 cytoplasmic tail and both are required for effective activation of integrin αIIbβ3 and resulting high-affinity ligand binding in platelets. However, binding of the talin head domain alone to β3 is sufficient to activate purified integrin αIIbβ3 in vitro. S...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Bryan N Kahner, Hisashi Kato, Asoka Banno, Mark H Ginsberg, Sanford J Shattil, Feng Ye
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2012-01-01
Цуврал:	PLoS ONE
Онлайн хандалт:	http://europepmc.org/articles/PMC3311585?pdf=render
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!