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Microglia–T cell interactions drive α-synuclein pathology in a Parkinson’s disease mouse model

Abstract Parkinson’s disease (PD), the second most prevalent neurodegenerative disorder, is characterized by motor dysfunction, progressive dopaminergic (DA) neuron loss in the substantia nigra, and the pathological accumulation of α-synuclein (αSyn) aggregates within Lewy bodies. Emerging evidence...

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Bibliografische gegevens
Hoofdauteurs: Yosuke Ohtake, Nana Norikami, Bin Hong, Kyoka Manabe, Takahide Itokazu, Toshihide Yamashita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2026-02-01
Reeks:Journal of Neuroinflammation
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Online toegang:https://doi.org/10.1186/s12974-026-03734-1
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