Chemical Modification of Auranofin Yields a New Family of Anticancer Drug Candidates: The Gold(I) Phosphite Analogues

A panel of four novel gold(I) complexes, inspired by the clinically established gold drug auranofin (1-Thio-β-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate), was prepared and characterized. All these compounds feature the replacement of the triethylphosphine ligand of the parent compo...

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Auteurs principaux:	Damiano Cirri, Andrea Geri, Lara Massai, Michele Mannelli, Tania Gamberi, Francesca Magherini, Matteo Becatti, Chiara Gabbiani, Alessandro Pratesi, Luigi Messori
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2023-01-01
Collection:	Molecules
Sujets:	auranofin metal-based drugs anticancer compounds phosphite compounds
Accès en ligne:	https://www.mdpi.com/1420-3049/28/3/1050
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