Causal association of plasminogen activators and their inhibitors with Alzheimer’s disease: a Mendelian randomization study

Introduction Alzheimer’s disease (AD) is the most common cause of dementia and contributes to a huge burden of disease worldwide. Observational studies have found that tissue plasminogen activator (t-PA) inhibits the development of AD, but little is known about urokinase plasminogen activator (u-PA)...

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Principais autores:	Xin Guo, Fangyu Gao, Baolong Pan, Feng Gao, Jingsi Zhang, Shanshan Wang, Qiao Niu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Termedia Publishing House 2024-08-01
coleção:	Archives of Medical Science
Assuntos:	mendelian randomization tissue plasminogen activator urokinase type plasminogen plasminogen activator inhibitor 1 alzheimer’s disease
Acesso em linha:	https://www.archivesofmedicalscience.com/Causal-association-of-plasminogen-activators-and-their-inhibitors-with-Alzheimer,192049,0,2.html
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