Functional Implications of Drosophila insulin-like peptides in metabolism, aging and dietary restriction

AbstractThe neuroendocrine architecture and insulin/insulin-like signaling (IIS) events in Drosophila are remarkably conserved. As IIS pathway governs growth and development, metabolism, reproduction, stress response and longevity; temporal, spatial and nutrient regulation of dilps encoding Drosoph...

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Hlavní autoři:	Kavitha ekannan, Yih-Woei eFridell
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2013-10-01
Edice:	Frontiers in Physiology
Témata:	Metabolism Lifespan Dietary restriction Drosophila insulin-like peptides Insulin-like peptide producing cells dFOXO
On-line přístup:	http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00288/full
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