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Expression of CXCL12-CXCR4/CXCR7 chemokines in splenic fibrosis of cirrhotic spleen and its therapeutic significance

Introduction To investigate the expression and treatment of chemokine CXCL12 and its receptor CXCR4/CXCR7. Methods The liver cirrhosis hypersplenism model of rats was made with CCL4, and then was detected by immunohistochemistry, Western blot and qRT-PCR. Results The area of spleen fibrosis in the...

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Principais autores: Yunfu Lv, Yejuan Li, XiaoYu Han, Ning Liu, Min Zeng
Format: Artigo
Sprog:Inglês
Udgivet: Termedia Publishing House 2023-08-01
Serier:Archives of Medical Science
Fag:
liver cirrhosis with hypersplenism
animal experiment
spleen fibrosis
chemotactic axis cxcl12-cxcr4/cxcr7
therapeutic significance
Online adgang:https://www.archivesofmedicalscience.com/Expression-of-CXCL12-CXCR4-CXCR7-chemokines-in-splenic-fibrosis-of-cirrhotic-spleen,170910,0,2.html
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