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IL-28B is a key regulator of B- and T-cell vaccine responses against influenza.

Influenza is a major cause of morbidity and mortality in immunosuppressed persons, and vaccination often confers insufficient protection. IL-28B, a member of the interferon (IFN)-λ family, has variable expression due to single nucleotide polymorphisms (SNPs). While type-I IFNs are well known to modu...

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Principais autores: Adrian Egli, Deanna M Santer, Daire O'Shea, Khaled Barakat, Mohammedyaseen Syedbasha, Madeleine Vollmer, Aliyah Baluch, Rakesh Bhat, Jody Groenendyk, Michael A Joyce, Luiz F Lisboa, Brad S Thomas, Manuel Battegay, Nina Khanna, Thomas Mueller, D Lorne J Tyrrell, Michael Houghton, Atul Humar, Deepali Kumar
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2014-12-01
סדרה:PLoS Pathogens
גישה מקוונת:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004556&type=printable
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