Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection.

Understanding the factors that delineate the efficacy of T cell responses towards pathogens is crucial for our ability to develop potent therapies against infectious diseases. Multidimensional evaluation of T cell functionality at the single-cell level enables exhaustive analysis of combinatorial fu...

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Bibliografske podrobnosti

Principais autores:	Anders Boyd, Jorge R Almeida, Patricia A Darrah, Delphine Sauce, Robert A Seder, Victor Appay, Guy Gorochov, Martin Larsen
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2015-01-01
Serija:	PLoS ONE
Online dostop:	http://europepmc.org/articles/PMC4457486?pdf=render
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