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Hemorheological Alterations and Oxidative Damage in Sickle Cell Anemia

Sickle cell anemia (SCA) is the most common hereditary disorder of hemoglobin (Hb) characterized by a mutation in the β globin gene, which leads to synthesis of HbS a hemoglobin which, under hypoxic conditions, gels and leading to the sickling of the red blood cells (RBC). The dehydration of the RBC...

Celý popis

Uloženo v:
Hlavní autoři: Patrizia Caprari, Sara Massimi, Loretta Diana, Francesco Sorrentino, Laura Maffei, Stefano Materazzi, Roberta Risoluti
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019-12-01
Edice:Frontiers in Molecular Biosciences
Témata:
sickle cell anemia
hemorheology
oxidative damage
erythrocyte deformability
erythrocyte membrane
On-line přístup:https://www.frontiersin.org/article/10.3389/fmolb.2019.00142/full
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