Downregulated MEG3 contributes to tumour progression and poor prognosis in oesophagal squamous cell carcinoma by interacting with miR-4261, downregulating DKK2 and activating the Wnt/β-catenin signalling

Long noncoding RNA (lncRNA) MEG3 has been widely reported to be decreased in a growing list of primary human tumours and play a key role in tumour suppression. However, there are few reports about MEG3 expression and function in oesophagal squamous cell carcinoma (ESCC). Here, we found that MEG3 exp...

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Principais autores:	Ji Ma, Teng-Fei Li, Xin-Wei Han, Hui-Feng Yuan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2019-12-01
coleção:	Artificial Cells, Nanomedicine, and Biotechnology
Assuntos:	Esophageal squamous cell carcinoma LncRNA MEG3 miR-4261 Dickkopf-2 Wnt/β-catenin signalling
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/21691401.2019.1602538
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