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N-Acetylcysteine Prevents Skeletal Muscle Cisplatin-Induced Atrophy by Inducing Myogenic microRNAs and Maintaining the Redox Balance

Cisplatin (CIS) is a widely used chemotherapeutic agent known for its efficacy; however, it induces several adverse effects, most notably cachexia, which is characterized by progressive loss of skeletal muscle mass, weakness, and reduced body weight. N-acetylcysteine (NAC) a compound with antioxidan...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Teminijesu Dorcas Aremu, Tonali Blanco Ayala, Karla F. Meza-Sosa, Daniela Ramírez Ortega, Dinora F. González Esquivel, Gustavo I. Vázquez Cervantes, Itamar Flores, Wendy Leslie González Alfonso, Verónica Custodio Ramírez, Alelí Salazar, Benjamin Pineda, Gonzalo Pérez de la Cruz, Saul Gómez Manzo, Gabriel Roldan Roldan, Paul Carrillo Mora, Verónica Pérez de la Cruz
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-11-01
Schriftenreihe:Antioxidants
Schlagworte:
myogenic microRNAs
myomiRs
redox environment
skeletal muscle
Online-Zugang:https://www.mdpi.com/2076-3921/14/11/1344
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