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Implementation of a high-throughput whole genome sequencing approach with the goal of maximizing efficiency and cost effectiveness to improve public health

ABSTRACTThis manuscript describes the development of a streamlined, cost-effective laboratory workflow to meet the demands of increased whole genome sequence (WGS) capacity while achieving mandated quality metrics. From 2020 to 2021, the Wadsworth Center Bacteriology Laboratory (WCBL) used a streaml...

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Autori principali: Michelle C. Dickinson, Samantha E. Wirth, Deborah Baker, Anna M. Kidney, Kara K. Mitchell, Elizabeth J. Nazarian, Matthew Shudt, Lisa M. Thompson, Sai Laxmi Gubbala Venkata, Kimberlee A. Musser, Lisa Mingle
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2024-04-01
Serie:Microbiology Spectrum
Soggetti:
whole genome sequencing
NextSeq
high throughput
workflow
DNA extraction
public health
Accesso online:https://journals.asm.org/doi/10.1128/spectrum.03885-23
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