Balanced engagement of activating and inhibitory receptors mitigates human NK cell exhaustion
NK cell exhaustion is caused by chronic exposure to activating stimuli during viral infection, tumorigenesis, and prolonged cytokine treatment. Evidence suggests that exhaustion may play a role in disease progression. However, relative to T cell exhaustion, the mechanisms underlying NK cell exhausti...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical investigation
2022-08-01
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| Seri Bilgileri: | JCI Insight |
| Konular: | |
| Online Erişim: | https://doi.org/10.1172/jci.insight.150079 |
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