Association of genetic risk of Alzheimer’s disease and cognitive function in two European populations

Abstract Although there is some evidence of an association between Alzheimer’s disease polygenic risk score (AD PRS) and cognitive function, limited validations have been performed in large populations. We investigated the relationship between AD PRS and cognitive function in the UK Biobank in over...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Biqi Wang, Lori B. Chibnik, Seung Hoan Choi, Deborah Blacker, Anita L. DeStefano, Honghuang Lin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-02-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Alzheimer’s disease Polygenic risk score Cognitive test Cohort
Online-Zugang:	https://doi.org/10.1038/s41598-025-90277-9
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