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Abundant Neural circRNA Cdr1as Is Not Indispensable for Retina Maintenance

Cdr1as is the abundant circular RNA (circRNA) in human and vertebrate retinas. However, the role of Cdr1as in the retina remains unknown. In this study, we aimed to generate a Cdr1as knockout (KO) mouse model and investigate the retinal consequences of Cdr1as loss of function. Through in situ hybrid...

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Autors principals: Xue-Jiao Chen, Meng-Lan Li, Ya-Han Wang, Hao Mou, Zhen Wu, Siqi Bao, Ze-Hua Xu, Hang Zhang, Xiao-Yun Wang, Chang-Jun Zhang, Xiangyang Xue, Zi-Bing Jin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020-11-01
Col·lecció:Frontiers in Cell and Developmental Biology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fcell.2020.565543/full
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