Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study

Objective: The mechanisms of chondrocytes ferroptosis in osteoarthritis (OA) have not yet been fully elucidated. This study aimed to identify key ferroptosis related genes (FRGs) involved in chondrocytes ferroptosis. Methods: LASSO, SVM-RFE, and receiver operating characteristic curve (ROC) were per...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Hong Sun, Guoxuan Peng, Kunhao Chen, Zhilin Xiong, Yong Zhuang, Miao Liu, Xu Ning, Hua Yang, Jin Deng
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2023-09-01
Rangatū:	Heliyon
Ngā marau:	Osteoarthritis Ferroptosis Biomarkers Ferroptosis related patterns Competing endogenous RNA EGFR
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S2405844023071839
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!