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Evaluating the Impact of gRNA SNPs in CasRx Activity for Reducing Viral RNA in HCoV-OC43

Viruses within a given family often share common essential genes that are highly conserved due to their critical role for the virus’s replication and survival. In this work, we developed a proof-of-concept for a pan-coronavirus CRISPR effector system by designing CRISPR targets that are cross-reacti...

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Detaylı Bibliyografya
Asıl Yazarlar: Cathryn Michelle Mayes, Joshua Santarpia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2022-06-01
Seri Bilgileri:Cells
Konular:
Online Erişim:https://www.mdpi.com/2073-4409/11/12/1859
Etiketler: Etiketle
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