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Altering rRNA 2’O-methylation pattern during neuronal differentiation is regulated by FMRP

The Fragile X Messenger Ribonucleoprotein (FMRP) is a selective RNA-binding protein that localizes to the cytoplasm and the nucleus. The loss of FMRP results in Fragile X Syndrome (FXS), an autism spectrum disorder. FMRP interacts with ribosomes and regulates the translation of mRNAs essential for n...

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Principais autores: Michelle Ninochka D’Souza, Naveen Kumar Chandappa Gowda, Nivedita Hariharan, Syed Wasifa Qadri, Dasaradhi Palakodeti, Ravi S Muddashetty
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2025-12-01
Serier:RNA Biology
Fag:
FMRP
ribosome
snoRNA
epitranscriptome
Ribosomal RNA
Online adgang:https://www.tandfonline.com/doi/10.1080/15476286.2025.2563986
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