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Jagged1 is Clinically Prognostic and Promotes Invasion of Glioma-Initiating Cells by Activating NF-κB(p65) Signaling

Background/Aims: Jagged1 is the ligands of the Notch signaling and has been shown to promote glioma-initiating cells (GICs) in glioblastoma. The role of Jagged1 in GICs invasion and underlying molecular mechanisms remain unclear. Methods: Survival data from R2 genomics analysis, the Cancer Genome At...

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Principais autores: Long Hai, Peidong Liu, Shengping Yu, Li Yi, Zhennan Tao, Chen Zhang, Iruni Roshanie Abeysekera, Tao Li, Luqing Tong, Haiwen Ma, Bo Liu, Yang Xie, Xingchen Zhou, Yu Lin, Meng Zhu, Kai Zhang, Bingcheng Ren, Haolang Ming, Yubao Huang, Xuejun  Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
coleção:Cellular Physiology and Biochemistry
Assuntos:
Jagged1
Glioma-initiating cells (GICs)
NF-κB(p65)
Invasion
Acesso em linha:https://www.karger.com/Article/FullText/496044
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