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Editing the Melanocortin-4 Receptor Gene in Channel Catfish Using the CRISPR-Cas9 System

The melanocortin-4 receptor (MC4R) plays a critical role in homeostasis and the regulation of body weight. Polymorphisms in the <i>mc4r</i> gene have been discovered and linked to growth, carcass composition, and meat quality traits. Therefore, we used the CRISPR-Cas9 system to target the <i>mc4r</i...

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Principais autores: Karim Khalil, Ahmed Elaswad, Hisham Abdelrahman, Maximillian Michel, Wenbiao Chen, Shikai Liu, Ramjie Odin, Zhi Ye, David Drescher, Khoi Vo, William S. Bugg, Guyu Qin, Yujia Yang, Nathan J. C. Backenstose, Zhanjiang Liu, Roger D. Cone, Rex Dunham
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-02-01
coleção:Fishes
Assuntos:
channel catfish
gene editing
CRISPR-Cas9
growth rate
feed conversion ratio
mutations
Acesso em linha:https://www.mdpi.com/2410-3888/8/2/116
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