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Pathophysiological Response to Hypoxia — From the Molecular Mechanisms of Malady to Drug Discovery: Drug Discovery for Targeting the Tumor Microenvironment

The tumor microenvironment, characterized by regions of hypoxia, low nutrition, and acidosis due to incomplete blood vessel networks, has been recognized as a major factor that influences not only the response to conventional anti-cancer therapies but also malignant progression and metastasis. Howev...

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Bibliografiske detaljer
Hovedforfatter: Hideko Nagasawa
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2011-01-01
Serier:Journal of Pharmacological Sciences
Online adgang:http://www.sciencedirect.com/science/article/pii/S1347861319307364
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