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FAM19A4 and miR124-2 methylation status in human papillomavirus-driven and human papillomavirus-negative oropharyngeal squamous cell carcinomas

Abstract Background Scarce data exist on host gene methylation in oropharyngeal squamous cell carcinomas (OPCs), which are caused by human papillomavirus (HPV) in approximately 40% of cases. We analyzed the methylation status of two host genes involved in cervical carcinogenesis, FAM19A4 and miR124-...

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Main Authors: Maria Gabriella Donà, Eugenia Giuliani, Valentina Laquintana, Renato Covello, Raul Pellini, Silvia Moretto, Alessandra Latini, Maria Benevolo, Francesca Rollo
Format: Artigo
Language:Inglês
Published: BMC 2025-10-01
Series:Infectious Agents and Cancer
Subjects:
HPV
Oropharyngeal neoplasms
Methylation
FAM19A4
miR124-2
Online Access:https://doi.org/10.1186/s13027-025-00697-5
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