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Temperature Sensitivity: A Potential Method for the Generation of Vaccines against the Avian Coronavirus Infectious Bronchitis Virus

The <i>Gammacoronavirus</i> infectious bronchitis virus (IBV) is a highly contagious economically important respiratory pathogen of domestic fowl. Reverse genetics allows for the molecular study of pathogenic determinants to enable rational vaccine design. The recombinant IBV (rIBV) Beau-R, a molecu...

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Principais autores: Sarah Keep, Phoebe Stevenson-Leggett, Angela Steyn, Michael S. Oade, Isobel Webb, Jamie Stuart, Lonneke Vervelde, Paul Britton, Helena J. Maier, Erica Bickerton
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-07-01
Series:Viruses
Assuntos:
coronavirus
IBV
temperature sensitivity
replicase
RNA synthesis
Acceso en liña:https://www.mdpi.com/1999-4915/12/7/754
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