From biomarker to targeted therapy: investigating trophoblast cell-surface antigen 2 expression in triple-negative breast cancer– insights from the national cancer institute

Abstract Background Triple-negative breast cancer (TNBC) is characterized by its aggressive behavior and limited treatment options, primarily due to the lack of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). TROP-2, a transmembr...

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Hlavní autoři:	Noura A. A. Ebrahim, Mustafa A. Hussein, Mohamed Emam Sobeih, Nancy H. Amin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-06-01
Edice:	BMC Cancer
Témata:	TROP-2 Triple-negative breast cancer Immunohistochemistry Precision oncology Prognostic biomarker
On-line přístup:	https://doi.org/10.1186/s12885-025-14402-7
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