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HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT)

<p>Abstract</p> <p>Background</p> <p>Activation of telomerase is a critical and late event in tumor progression. Thus, in patients with adult-T cell leukaemia (ATL), an HTLV-1 (Human T cell Leukaemia virus type 1)-associated disease, leukemic cells display a high telomerase activity, mainly through...

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Autori principali: Gazzolo Louis, Villaudy Julien, Kuhlmann Anne-Sophie, Castellazzi Marc, Mesnard Jean-Michel, Duc Dodon Madeleine
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2007-12-01
Serie:Retrovirology
Accesso online:http://www.retrovirology.com/content/4/1/92
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