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HTLV-1 modulates the frequency and phenotype of FoxP3<sup>+</sup>CD4<sup>+</sup> T cells in virus-infected individuals

<p>Abstract</p> <p>Background</p> <p>HTLV-1 utilizes CD4 T cells as the main host cell and maintains the proviral load via clonal proliferation of infected CD4<sup>+</sup> T cells. Infection of CD4<sup>+</sup> T cells by HTLV-1 is therefore thought to play a pivotal role in HTLV-1-related pathogenic...

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Auteurs principaux: Satou Yorifumi, Utsunomiya Atae, Tanabe Junko, Nakagawa Masanori, Nosaka Kisato, Matsuoka Masao
Format: Artigo
Langue:Inglês
Publié: BMC 2012-05-01
Collection:Retrovirology
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Accès en ligne:http://www.retrovirology.com/content/9/1/46
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