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New Insights into the Bioenergetic and Immunomodulatory Properties of Phospholipases A<sub>2</sub> from <i>Bothrops diporus</i> Venom

Phospholipases A<sub>2</sub> (PLA<sub>2</sub>s) are key mediators of the cytotoxic and inflammatory activities of <i>snake</i> venoms. While PLA<sub>2</sub> isoforms from <i>Bothrops diporus</i> venom have been characterized and shown to possess antimetastatic and antiangiogenic properties, their im...

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Gardado en:
Principais autores: Daniela J. Sasovsky, Ana K. Oliveira, Dilza Trevisan Silva, Gonzalo A. Ojeda, Cristopher Almarza, Bruno Lomonte, Jay W. Fox, Félix A. Urra, Soledad Bustillo
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2026-02-01
Series:Toxins
Assuntos:
<i>Bothrops diporus</i>
phospholipases A<sub>2</sub>
mitochondrial dysfunction
cytokine modulation
immunometabolism
Acceso en liña:https://www.mdpi.com/2072-6651/18/2/114
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