Bile Salt Hydrolase Degrades β-Lactam Antibiotics and Confers Antibiotic Resistance on Lactobacillus paragasseri

Bile salt hydrolase (BSH) is a well-characterized probiotic enzyme associated with bile detoxification and colonization of lactic acid bacteria in the human gastrointestinal tract. Here, we isolated a putative BSH (LpBSH) from the probiotic bacterium Lactobacillus paragasseri JCM 5343T and demonstra...

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Detalhes bibliográficos

Principais autores:	Hiroyuki Kusada, Masanori Arita, Masanori Tohno, Hideyuki Tamaki
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-06-01
coleção:	Frontiers in Microbiology
Assuntos:	antibiotic resistance bile salt hydrolase Lactobacillus paragasseri Ntn-hydrolase family protein penicillin acylase
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2022.858263/full
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