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Safety and efficacy of PEG-rhG-CSF as primary prophylaxis for neutropenia in gastrointestinal cancer patients receiving combination chemotherapy including oral agents: a prospective, exploratory, non-randomized controlled study

PurposeThe safety and efficacy of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) for prevention of chemotherapy-induced neutropenia (CIN) in patients undergoing oral chemotherapy remain unclear. This study aimed to investigate the safety and efficacy of PEG-rhG-CSF a...

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Principais autores: Hui Wang, Xiaoling Zhang, Yunyi Du, Min Liu, Ning Ma, Yangjun Gao, Mei Wang, Linlin Cai, Tingting Feng, Suxia Yang, Wenqing Hu, Gehong Zhang, Jun Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-04-01
coleção:Frontiers in Oncology
Assuntos:
chemotherapy-induced neutropenia
gastrointestinal neoplasms
oral chemotherapy agents
PEG-rhG-CSF
primary prophylaxis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2026.1764358/full
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