Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse
Congenital ocular malformations originate from defective morphogenesis during early eye development and cause 25% of childhood blindness. Formation of the eye is a multi-step, dynamic process; it involves evagination of the optic vesicle, followed by distal and ventral invagination, leading to the f...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2024-11-01
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| Serier: | Frontiers in Cellular Neuroscience |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fncel.2024.1474010/full |
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