The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons

Proper transport of the Parkinson’s disease (PD) protein, α-synuclein (α-syn), is thought to be crucial for its localization and function at the synapse. Previous work has shown that defects in long distance transport within narrow caliber axons occur early in PD, but how such defects contribute to...

Descripció completa

Dades bibliogràfiques

Autors principals:	Eric N. Anderson, Delnessaw Hirpa, Kan Hong Zheng, Rupkatha Banerjee, Shermali Gunawardena
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2020-01-01
Col·lecció:	Frontiers in Cellular Neuroscience
Matèries:	α-synuclein (a-synuclein) axonal transport disruption Parkinson’s disease synaptic abnormality in vivo imaging
Accés en línia:	https://www.frontiersin.org/article/10.3389/fncel.2019.00540/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!