Müller glia derived EVs promote neurite recovery of an enriched population of retinal ganglion like cells derived from hESC retinal organoids after damage

Abstract Membrane-bound extracellular vesicles (EVs) released by Müller glia contain microRNA (miRNA) and proteins with the potential to be beneficial in providing neuroprotection in retinal degenerative conditions. The aim of this study was to examine the neuroprotective effect of Müller glia deriv...

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Bibliografische Detailangaben

Hauptverfasser:	Karen Eastlake, William D. B. Lamb, Dhani Tracey-White, Keiichi Shibagaki, Peng T. Khaw, Hari Jayaram, G. Astrid Limb
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-03-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Muller glia Retina Stem cells Retinal organoids Retinal ganglion cells Degeneration
Online-Zugang:	https://doi.org/10.1038/s41598-026-42089-8
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