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Gut microbiota community and metabolic profiles in direct total cavopulmonary connection and Fontan circulation: a cross-sectional study in the single center

BackgroundThis study aimed to evaluate the impact of the direct total cavopulmonary connection (dTCPC) procedure on the gut microbiome and metabolome. It also sought to elucidate the features of the gut microbiota community and metabolic profiles in Fontan circulation.MethodsWe randomly recruited 45...

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Principais autores: Kaiyu Wang, Linjiang Han, Jianrui Ma, Yushen Fang, Yinru He, Xiaobing Liu, Shusheng Wen, Jian Zhuang, Haiyun Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-03-01
Serier:Frontiers in Microbiology
Fag:
direct total cavopulmonary connection
Fontan procedure
microbiome
metabolome
congenital heart surgery
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1539046/full
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