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Gut microbiome affects the metabolism of metronidazole in mice through regulation of hepatic cytochromes P450 expression.

Microbiome is now considered as a significant metabolic organ with an immense potential to influence overall human health. A number of diseases that are associated with pharmacotherapy interventions was linked with altered gut microbiota. Moreover, it has been reported earlier that gut microbiome mo...

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Bibliographic Details
Main Authors: Nina Zemanová, Kateřina Lněničková, Markéta Vavrečková, Eva Anzenbacherová, Pavel Anzenbacher, Iveta Zapletalová, Petra Hermanová, Tomáš Hudcovic, Hana Kozáková, Lenka Jourová
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0259643
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