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Differential association of the conserved SUMO ligase Zip3 with meiotic double-strand break sites reveals regional variations in the outcome of meiotic recombination.

During the first meiotic prophase, programmed DNA double-strand breaks (DSBs) are distributed non randomly at hotspots along chromosomes, to initiate recombination. In all organisms, more DSBs are formed than crossovers (CO), the repair product that creates a physical link between homologs and allow...

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Detalhes bibliográficos
Principais autores: Maria-Elisabetta Serrentino, Emmanuel Chaplais, Vérane Sommermeyer, Valérie Borde
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-04-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC3616913?pdf=render
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