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Regulation of the Activity of the Dual Leucine Zipper Kinase by Distinct Mechanisms

The dual leucine zipper kinase (DLK) alias mitogen-activated protein 3 kinase 12 (MAP3K12) has gained much attention in recent years. DLK belongs to the mixed lineage kinases, characterized by homology to serine/threonine and tyrosine kinase, but exerts serine/threonine kinase activity. DLK has been...

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Principais autores: Kyra-Alexandra Köster, Marten Dethlefs, Jorge Duque Escobar, Elke Oetjen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-02-01
coleção:Cells
Assuntos:
dual leucine zipper kinase
phosphorylation
protein–protein interaction
proteasomal degradation
palmitoylation
Acesso em linha:https://www.mdpi.com/2073-4409/13/4/333
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